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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery in renal transplantation: a case report

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《医学前沿(英文)》 2012年 第6卷 第3期   页码 329-331 doi: 10.1007/s11684-012-0211-9

摘要:

Ischemic postconditioning was defined as rapid intermittent interruptions of blood ?ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusion injury (IRI) in animal models but not in clinical trials. We describe a case that the allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemia of allograft after reperfusion. The allograft restored blood flow without second reperfusion and cold preservation after 9 min of warm ischemia. The patient was followed up for 3 months and the allograft worked well without complications.

关键词: renal transplantation     vein twist     ischemia-reperfusion injury    

Correlation of Twist upregulation and senescence bypass during the progression and metastasis of cervical

null

《医学前沿(英文)》 2014年 第8卷 第1期   页码 106-112 doi: 10.1007/s11684-014-0307-5

摘要:

Cervical carcinoma is associated with high propensity for local invasion and lymph node metastasis. However, the molecular alterations that drive progression and metastasis of cervical cancer remain unclear. Cellular senescence has been proposed as the mechanism that protects an organism against cancer progression and metastasis. In addition, Twist, a basic helix-loop-helix transcription factor, has been suggested as an oncogene because it is overexpressed in many types of human cancer. This gene also exhibits a positive function in regulating invasion and metastasis. In this study, Twist was strongly and positively expressed in normal tissue, squamous cell carcinoma (SCC) IA--IIA, and SCC IIB--IIIB (4.3%, 44%, and 88.9%, respectively). The strong positive expressions of the senescence marker CBX3 were 39.1%, 32%, and 15.6%, respectively. The strong positive expressions of Twist in the SCC groups with or without lymph node metastasis were 80.8% and 50%. For CBX3, such expressions were 7.7% and 29.5%, respectively. Results also showed that the expression of Twist was inversely correlated with that of CBX3. Moreover, the knockdown of Twist with target siRNA in SiHa triggered the induction of the chromatin marker of the cellular senescence CBX3 and senescence-associated β-galactosidase activity. Our results suggested that the expression of Twist increased during the progression and metastasis of cervical cancer. Furthermore, Twist-induced senescence bypass is important in this process.

关键词: cervical cancer     senescence     Twist     CBX3     lymph node metastasis    

Successful infrainguinal revascularization with autologous vein for inadvertent stripping of superficial

Yin XIA MD , Dan SHANG MD, PhD , Qin LI MD , Wenyi LI MD , Hanqing WU MD , Guofu HU MD , Chao YANG MD , Yiqing LI MD , Bi JIN MD ,

《医学前沿(英文)》 2009年 第3卷 第3期   页码 375-378 doi: 10.1007/s11684-009-0048-z

摘要: A referral patient who had previously undergone varicose vein surgery was admitted as an emergency case. On admission, the patient complained of intolerable pain, paralysis and paresthesia of the affected limb, which was characterized by acute arterial ischemia symptoms. Color Doppler of the artery of the affected limb indicated that no blood flow signal existed in the superficial femoral artery. During exploratory operation, we found that the right superficial femoral artery instead of the great saphenous vein of the affected limb had been stripped and ligated. Therefore, the intact right great saphenous vein was taken for auto-transplantation by inverse end-to-end anastomosis to the proximal and distal residual superficial femoral artery, which resulted in gradual recovery. Except for ischemic reperfusion injury, no other post-operative complications occurred after a 10 month follow-up; however, the long-term curative effect needs further observation. Here we report our treatment experience.

关键词: revascularization     saphenous vein     end-to-end anastomosis     stripping    

Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

《医学前沿(英文)》 2007年 第1卷 第2期   页码 196-199 doi: 10.1007/s11684-007-0037-z

摘要: The aim of this paper was to investigate the effects of resistin on human umbilical vein endothelial cells (HUVECs), and to explore its role and mechanism of action in atherosclerosis. HUVECs were incubated with recombinant human resistin (0, 50, 100 ng/mL) for 24 h. ICAM-1, VCAM-1 and reactive oxygen species (ROS) were assayed by flow cytometer. ET-1, eNOS and iNOS mRNA expression were measured by semi-quantitative RT-PCR. Incubation of HUVECs with resistin resulted in an increase in ICAM-1 expression and ET-1 mRNA expression. However, resistin had no effect on VCAM-1 expression and ROS release. eNOS and iNOS mRNA expression were not altered by resistin stimulation. Adipokine resistin exerted a direct effect in promoting HUVEC dysfunction by promoting ICAM-1 and ET-1 expression. These data suggest that adipocyteendothelium cross-talk might play an important role in the pathogenesis of cardiovascular disease in diabetes mellitus.

关键词: endothelial     resistin stimulation     Incubation     pathogenesis     dysfunction    

基于刚性与非刚性Square-Twist胞元混合排布的折纸超材料设计与性能编程研究 Article

马家耀, 臧世玺, 陈焱, 由衷

《工程(英文)》 2022年 第17卷 第10期   页码 82-92 doi: 10.1016/j.eng.2022.02.015

摘要: 本文通过将一系列不同类型的square-twist 折纸胞元进行空间排布,设计了一种新型折纸超材料。首先建立了超材料胞元的空间排布规则,保证了相邻胞元山-谷线折痕的几何匹配。

关键词: 折纸超材料     超材料     square-twist折纸     非周期性排布     可编程性    

Assessment of global and regional left ventricular twist and displacement in anterior myocardial infarction

Wei HAN MM, Ming-Xing XIE MD, Qing LV MD, Xin-Fang WANG MD, Li ZHANG MM,

《医学前沿(英文)》 2010年 第4卷 第1期   页码 71-76 doi: 10.1007/s11684-010-0006-9

摘要: The recent development of 2-dimensional strain (2D strain) imaging can provide a powerful alternative for assessing left ventricular (LV) torsion. This study was conducted to evaluate the global and regional left ventricular twist by 2D strain in patients with anterior wall myocardial infarction (AMI). A total of 55 AMI patients were divided into two groups according to their ejection fraction (EF) values (group A: LVEF≥50%; group B: LVEF<50%), and 35 normal people served as the control group. Using 2-dimensional strain software, global and regional LV rotation and displacement were obtained at two planes. Compared with the control group, patients of group A showed reduced peak LV twist of the anterior and anterior-septal wall (9.26±1.89 10.74±2.67; 9.71±1.71 11.36±2.29, both <0.05), but the radial displacement and global twist were maintained (>0.05). Differently, regional and global LV twist and radial displacement in patients of group B deceased significantly, especially in the anterior and anterior-septal wall, as compared with patients in the control or group A (both <0.05). Moreover, a strong correlation was noted between peak twist and radial displacement; the twist-displacement loop was markedly distorted in patients of group B. This study demonstrated that 2D strain has a potential ability for quantification of left ventricular global and segment twist and radial displacement in patients with coronary artery disease.

关键词: echocardiography     twist     two-dimensional strain imaging     coronary artery disease    

Vein of Galen malformations - report of 2 cases and literature review

CAI Chunquan, ZHANG Qingjiang, SHEN Changhong

《医学前沿(英文)》 2008年 第2卷 第3期   页码 317-322 doi: 10.1007/s11684-008-0061-7

摘要: Vein of Galen malformations (VGMs) are rare, consisting approximately 1% of intracranial vascular malformations, but nearly one third of pediatric vascular malformations, which can cause severe morbidity and mortality in infants and older children, but more particularly in neonates. We presented 2 patients with VGMs which were confirmed by characteristic clinical symptoms and neuroradiological findings (including CT, MRI and/or angiography). One patient underwent embolization followed by CT, MRI and conventional angiography. The patient’s neurological and cognitive status was normal at present. The other neonate died of congestive heart failure 36 h after birth.

关键词: underwent embolization     angiography     pediatric vascular     cognitive     characteristic    

标题 作者 时间 类型 操作

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery in renal transplantation: a case report

null

期刊论文

Correlation of Twist upregulation and senescence bypass during the progression and metastasis of cervical

null

期刊论文

Successful infrainguinal revascularization with autologous vein for inadvertent stripping of superficial

Yin XIA MD , Dan SHANG MD, PhD , Qin LI MD , Wenyi LI MD , Hanqing WU MD , Guofu HU MD , Chao YANG MD , Yiqing LI MD , Bi JIN MD ,

期刊论文

Study on the action of resistin-induced human umbilical vein endothelial cell dysfunction

LI Zhizhen, LI Fangping, YAN Li, LI Feng, LI Yan, CHENG Hua, FU Zuzhi

期刊论文

基于刚性与非刚性Square-Twist胞元混合排布的折纸超材料设计与性能编程研究

马家耀, 臧世玺, 陈焱, 由衷

期刊论文

Assessment of global and regional left ventricular twist and displacement in anterior myocardial infarction

Wei HAN MM, Ming-Xing XIE MD, Qing LV MD, Xin-Fang WANG MD, Li ZHANG MM,

期刊论文

Vein of Galen malformations - report of 2 cases and literature review

CAI Chunquan, ZHANG Qingjiang, SHEN Changhong

期刊论文